SCHEMBL14367151

SCHEMBL14367151

C=C/C(O)=C\CCCC=O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.48
TSHR P16473 2/20 0.35
MAPT P10636 1/20 0.31
TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutaral SCHEMBL29189724 0.77 HIF1A (0.56) HIF1ATSHRMAPTTRPV1
Glutaral SCHEMBL5868481 0.76
SCHEMBL2332708 0.75
SCHEMBL5082317 0.73
SCHEMBL5082315 0.73
SCHEMBL6066079 0.73 TBXAS1 (0.32)
Acrylic Acid SCHEMBL29428193 0.72 LMNA (0.56) HIF1ATSHRMAPTTRPV1
SCHEMBL868510 0.71 EP300 (0.48) TSHRMAPT
Glutaral SCHEMBL27983219 0.70 TSHR (0.58) HIF1ATSHRMAPTTRPV1
Glutaral SCHEMBL9500026 0.70 HIF1A (0.71) HIF1ATSHRMAPTTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070298481-A1 Method for Producing a Useful Intermediate in Alkaloid Biosynthesis By Using Rnai Technology KYOTO UNIVERSITY (JP) 2007-12-27 US disclosed