Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547894 | 0.87 | ALDH1A1 (0.45) | ALDH1A1LMNARECQLKMT2AMAPT | |
| SCHEMBL12028950 | 0.87 | SMN1; SMN2 (0.48) | KDM4ETDP1ALDH1A1LMNARECQL | |
| SCHEMBL4547895 | 0.86 | SMN1; SMN2 (0.50) | KDM4ETDP1ALDH1A1LMNARECQL | |
| SCHEMBL12028951 | 0.84 | SMN1; SMN2 (0.51) | ALDH1A1LMNARECQLKMT2AMAPT | |
| SCHEMBL3085138 | 0.79 | ALDH1A1 (0.67) | KDM4ETDP1ALDH1A1LMNARECQL | |
| SCHEMBL32667239 | 0.79 | KDM4E (0.58) | KDM4ETDP1ALDH1A1LMNARECQL | |
| SCHEMBL10891097 | 0.79 | RECQL (0.50) | KDM4ETDP1ALDH1A1LMNARECQL | |
| SCHEMBL2112989 | 0.78 | TDP1 (0.49) | KDM4ETDP1ALDH1A1LMNARECQL | |
| SCHEMBL22079383 | 0.75 | SMN1; SMN2 (0.49) | KDM4ETDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14367258 | 0.75 | KMT2A (0.47) | KDM4ETDP1ALDH1A1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |