Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085138 | 0.79 | ALDH1A1 (0.67) | KMT2AMEN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL10891097 | 0.79 | RECQL (0.50) | KMT2AMEN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL32667239 | 0.79 | KDM4E (0.58) | KMT2AKDM4ETDP1ALDH1A1PDE2A | |
| SCHEMBL2112989 | 0.78 | TDP1 (0.49) | KMT2AKDM4ETDP1ALDH1A1POLB | |
| SCHEMBL14367255 | 0.75 | KDM4E (0.46) | KMT2AKDM4ETDP1ALDH1A1POLB | |
| SCHEMBL22079383 | 0.75 | SMN1; SMN2 (0.49) | KDM4ETDP1ALDH1A1LMNAOGA | |
| SCHEMBL20071345 | 0.74 | RET (0.41) | KMT2AMEN1ALDH1A1MAPK1PDE2A | |
| SCHEMBL13333198 | 0.70 | FDPS (0.38) | KMT2AMEN1TDP1ALDH1A1MAPK1 | |
| SCHEMBL24862745 | 0.70 | OGA (0.57) | KMT2AMEN1KDM4ETDP1ALDH1A1 | |
| SCHEMBL22079378 | 0.70 | SMN1; SMN2 (0.53) | OGASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |