Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12460733 | 0.89 | ITGB3 (0.57) | L3MBTL1MAPTITGB3ITGA2BTP53 | |
| SCHEMBL7292456 | 0.89 | HTT (0.52) | L3MBTL1MAPTITGB3ITGA2B | |
| SCHEMBL8175391 | 0.89 | ITGB3 (0.49) | L3MBTL1MAPTNPC1RAB9AITGB3 | |
| SCHEMBL8174116 | 0.89 | MAPT (0.48) | L3MBTL1MAPTITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7294390 | 0.89 | LTA4H (0.53) | L3MBTL1MAPTTDP1SMN1; SMN2 | |
| SCHEMBL7302421 | 0.88 | PPARA (0.55) | L3MBTL1MAPTITGB3ITGA2B | |
| SCHEMBL8177159 | 0.88 | ITGB3 (0.51) | L3MBTL1MAPTNPC1RAB9AITGB3 | |
| SCHEMBL7293967 | 0.88 | LTA4H (0.54) | L3MBTL1MAPTITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL8180158 | 0.88 | MAPT (0.49) | L3MBTL1MAPTMEN1KMT2AITGB3 | |
| SCHEMBL7297510 | 0.87 | PPARA (0.54) | L3MBTL1MAPTHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |