Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 11/20 | 0.56 |
| ▸ | MAOA | P21397 | 4/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5885604 | 0.91 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL7149558 | 0.91 | MAOB (0.58) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL31533148 | 0.87 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL31591495 | 0.87 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL435043 | 0.87 | ALDH1A1 (0.61) | ALDH1A1MAPTMAOBMAOATUBB1 | |
| SCHEMBL21370452 | 0.85 | NPC1 (0.61) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL15474693 | 0.84 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL5290849 | 0.83 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL7146795 | 0.82 | MAOB (0.58) | ALDH1A1L3MBTL1LMNAMAPTHPGD | |
| SCHEMBL25222497 | 0.82 | TUBB1 (0.55) | ALDH1A1LMNAMAPTHPGDTUBB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297796-B2 | Sulfamoyl benzamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |