Sugi Predict

Sugi Predict / Compounds / SCHEMBL435043

SCHEMBL435043

SCHEMBL435043

COc1cc(OCc2ccccc2)ccc1C=O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.61
▸ ERN1 O75460 3/20 0.59
▸ TUBB1 Q9H4B7 1/20 0.57
▸ MAOB P27338 2/20 0.54
▸ MAOA P21397 1/20 0.54
▸ NPC1 O15118 1/20 0.52
▸ RAB9A P51151 1/20 0.52
▸ TDP1 Q9NUW8 1/20 0.52
▸ HDAC8 Q9BY41 1/20 0.52
▸ MAPT P10636 2/20 0.51
▸ KDM4E B2RXH2 1/20 0.51
▸ POLB P06746 1/20 0.51
▸ HTT P42858 1/20 0.51
▸ RECQL P46063 1/20 0.51
▸ NPSR1 Q6W5P4 1/20 0.51
▸ APP P05067 1/20 0.50
▸ PDGFRB P09619 1/20 0.50
▸ PDGFRA P16234 1/20 0.50
▸ ALOX5 P09917 1/20 0.49
▸ PTPN1 P18031 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5885604 0.90 ALDH1A1 (0.68) ALDH1A1ERN1TUBB1MAOBNPC1
SCHEMBL865350 0.89 MAOA (0.58) ERN1MAOBMAOANPC1RAB9A
SCHEMBL6035502 0.88 TUBB1 (0.72) ALDH1A1ERN1TUBB1MAOBMAOA
SCHEMBL1311076 0.88 HDAC8 (0.65) ALDH1A1ERN1MAOBNPC1RAB9A
SCHEMBL7228424 0.87 CCNB2 (0.61) ERN1TUBB1MAOBHDAC8MAPT
SCHEMBL6690276 0.87 ALDH1A1 (0.65) ALDH1A1ERN1TUBB1MAOBNPC1
SCHEMBL7228421 0.87 CCNB2 (0.61) ERN1TUBB1MAOBHDAC8MAPT
SCHEMBL1445747 0.87 MAOB (0.50) ALDH1A1ERN1TUBB1MAOBMAOA
SCHEMBL14367331 0.87 ALDH1A1 (0.60) ALDH1A1ERN1TUBB1MAOBMAOA
SCHEMBL3370062 0.87 MAOB (0.52) ERN1TUBB1MAOBMAOANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117239231-A Electrolyte additive for lithium battery, electrolyte and preparation method of electrolyte 哈尔滨工业大学 2023-12-15 — — CN claimed
JP-2002523448-A — — 2002-07-30 — — JP claimed
US-6410540-B1 HEART AND KIDNEY DISEASES; ANTIINFLAMMATORY AGENTS SCIOS, INC. 2002-06-25 — — US claimed
EP-1107758-A2 USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE SCIOS INC. (US) 2001-06-20 — — EP claimed
WO-2000012074-A2 USE OF PIPERIDINES AND/OR PIPERAZINES AS INHIBITORS OF P38-ALPHA KINASE SCIOS INC. (US) 2000-03-09 — — WO claimed
EP-4603488-A1 NOVEL INDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF Korea University Research and Business Foundation (KR) 2025-08-20 — — EP disclosed
CN-120035587-A Novel indazole derivative or pharmaceutically acceptable salt thereof and use thereof 高丽大学校产学协力团 2025-05-23 — — CN disclosed
US-20250154104-A1 SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH ALONBIO LTD. (IL) 2025-05-15 — — US disclosed
CN-119977884-A Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death 阿龙拜欧有限公司 2025-05-13 — — CN disclosed
EP-4524131-A1 SMALL MOLECULES FOR TREATING CANCER, INHABITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH AlonBio Ltd. (IL) 2025-03-19 — — EP disclosed
CN-114096524-B Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death 阿龙拜欧有限公司 2025-03-04 — — CN disclosed
US-12202803-B2 Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death ALONBIO LTD. (IL) 2025-01-21 — — US disclosed
US-20040110807-A1 Thiazole derivatives HOFFMANN-LA ROCHE INC. 2004-06-10 — — US disclosed
WO-2004041275-A1 SUBSTITUTED 4-ALKOXYOXAZOL DERIVATIVES AS PPAR AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2004-05-21 — — WO disclosed
WO-2004031162-A1 CHIRALE OXAZOLE-ARYLPROPIONIC ACID DERIVATIVES AND THEIR USE AS PPAR AGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2004-04-15 — — WO disclosed
CN-1487940-A Lactam compounds and pharmaceutical use thereof ֮����ʽ���� 2004-04-07 — — CN disclosed
US-20040048847-A1 Lactam compounds and pharmaceutical use thereof AJINOMOTO CO. INC (JP) 2004-03-11 — — US disclosed
WO-2004020420-A1 NOVEL 2-ARYLTHIAZOLE COMPOUNDS AS PPARALPHA AND PPARGAMA AGONISTS F.HOFFMANN-LA ROCHE AG (CH) 2004-03-11 — — WO disclosed
WO-2004007453-A1 PIPERIDINETRIOL DERIVATIVES AS INHIBITORS OF GLYCOSYLCERAMIDE SYNTHASE OXFORD GLYCOSCIENCES (UK) LTD (GB) 2004-01-22 — — WO disclosed
EP-1346993-A1 LACTAM COMPOUNDS AND MEDICINAL USE THEREOF Ajinomoto Co., Inc. (JP) 2003-09-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250154104-A1 SMALL MOLECULES FOR TREATING CANCER, INHIBITING CHEMOKINE ACTIVITY AND/OR INDUCING CELL DEATH CCL2, CXCR2, CCL5 ALDH1A1 1330/4885ERN1 1175/4885TUBB1 2318/4885
US-20040048847-A1 Lactam compounds and pharmaceutical use thereof SLC2A4, SLC2A8, SLC2A1 ALDH1A1 911/4885ERN1 2414/4885TUBB1 2015/4885
US-20040110807-A1 Thiazole derivatives SLC5A1, GPR119, INSR ALDH1A1 274/4885ERN1 219/4885TUBB1 1517/4885
US-12202803-B2 Small molecules for treating cancer, inhibiting chemokine activity and/or inducing cell death CCL2, CXCR2, CCL5 ALDH1A1 1330/4885ERN1 1175/4885TUBB1 2318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.