Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | CA6 | P23280 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5622967 | 0.87 | HSP90AA1 (0.53) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL5624335 | 0.78 | CNR2 (0.46) | APPTEX264TP53MAPTLMNA | |
| SCHEMBL5623824 | 0.76 | P2RX7 (0.54) | APPTEX264TP53MAPTLMNA | |
| SCHEMBL5795987 | 0.75 | P2RX7 (0.53) | APPTEX264TP53KMT2AMAPT | |
| SCHEMBL5626386 | 0.73 | CNR2 (0.68) | TP53MAPTCNR2 | |
| SCHEMBL11712969 | 0.73 | KMT2A (0.71) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL15076647 | 0.72 | CA1 (0.72) | CA12CA1CA2CA3CA4 | |
| SCHEMBL16246408 | 0.71 | CFTR (0.68) | TP53MEN1KMT2AMAPTLMNA | |
| SCHEMBL10770155 | 0.69 | CA12 (0.53) | APPTEX264TP53MEN1KMT2A | |
| SCHEMBL14025362 | 0.69 | MEN1 (0.62) | TP53MEN1KMT2ALMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297796-B2 | Sulfamoyl benzamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |