Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 8/20 | 0.53 |
| ▸ | HRH1 | P35367 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1714830 | 0.99 | DRD2 (0.53) | DRD2HRH2HRH1KDM4EHRH3 | |
| SCHEMBL14367487 | 0.83 | DRD2 (0.56) | DRD2HRH2HRH1KDM4EHRH3 | |
| Acetic Acid SCHEMBL5624244 | 0.81 | KDM4E (0.57) | DRD2HRH2HRH1KDM4EHRH3 | |
| SCHEMBL14367305 | 0.81 | PLK1 (0.56) | RAB9A | |
| SCHEMBL1714559 | 0.80 | PRSS1 (0.69) | DRD2HRH3CHRM2HTR2AKCNH2 | |
| SCHEMBL18296656 | 0.80 | PRSS1 (0.41) | HRH3CHRM2HTR2AKCNH2 | |
| SCHEMBL14367450 | 0.80 | HRH3 (0.47) | DRD2HRH2HRH1KDM4EHRH3 | |
| Hydrochloric Acid SCHEMBL1714997 | 0.79 | PRSS1 (0.70) | DRD2HRH3CHRM2HTR2AKCNH2 | |
| Hydrochloric Acid SCHEMBL1715417 | 0.79 | HRH3 (0.46) | DRD2HRH2HRH1KDM4EHRH3 | |
| SCHEMBL12461388 | 0.78 | PRSS1 (0.51) | HRH3CHRM2HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |