Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HRH2 | P25021 | 7/20 | 0.56 |
| ▸ | HRH1 | P35367 | 7/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5624244 | 0.97 | KDM4E (0.57) | DRD2KDM4EHRH2HRH1HRH3 | |
| SCHEMBL5624249 | 0.90 | HRH2 (0.50) | DRD2KDM4EHRH2HRH1HRH3 | |
| SCHEMBL14367448 | 0.83 | DRD2 (0.54) | DRD2KDM4EHRH2HRH1HRH3 | |
| SCHEMBL14367306 | 0.83 | TP53 (0.54) | KDM4E | |
| Hydrochloric Acid SCHEMBL1714830 | 0.82 | DRD2 (0.53) | DRD2KDM4EHRH2HRH1HRH3 | |
| SCHEMBL14367498 | 0.80 | ITGB3 (0.54) | KDM4EHRH2HRH1HRH3 | |
| Hydrochloric Acid SCHEMBL1714169 | 0.80 | ITGB3 (0.54) | KDM4EHRH2HRH1HRH3 | |
| SCHEMBL14367515 | 0.79 | ITGB3 (0.61) | KDM4EHRH2HRH1HRH3 | |
| SCHEMBL1715294 | 0.77 | HRH3 (0.50) | DRD2KDM4EHRH2HRH1HRH3 | |
| SCHEMBL5623727 | 0.77 | ITGB3 (0.58) | KDM4EHRH2HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291617-B2 | Arylamidine derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |