Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RHEB | Q15382 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20787024 | 0.93 | CXCL8 (0.49) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9768108 | 0.91 | ALDH1A1 (0.50) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11122698 | 0.86 | ALDH1A1 (0.46) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL9454010 | 0.86 | AKR1B1 (0.43) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1436765 | 0.85 | HPGD (0.59) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL10932438 | 0.84 | CXCL8 (0.45) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| Bromide SCHEMBL28304801 | 0.83 | HPGD (0.57) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1532088 | 0.82 | ALDH1A1 (0.54) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL4951960 | 0.81 | TSHR (0.56) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL27429370 | 0.80 | ALDH1A1 (0.52) | CXCL8HPGDSLC6A2SLC6A3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | claimed |
| WO-1996037535-A1 | METHOD OF PREPARING POLY(PHENYLENE OXIDES) IN CARBON DIOXIDE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-28 | — | — | WO | disclosed |
| US-5250486-A | Catalyst comprising a manganese compound, a chelate compound, a base and an unsaturated ketone or ether; controlled molecular weight; odorless; stabile thermal properties when blended with styrene resins | GENERAL ELECTRIC COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0255230-B1 | PROCESS FOR PRODUCING POLYPHENYLENE ETHERS | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1992-10-14 | — | — | EP | disclosed |
| EP-0491190-A2 | Polyphenylene ether process and resin composition | GENERAL ELECTRIC COMPANY (US) | 1992-06-24 | — | — | EP | disclosed |
| US-5037943-A | Oxidative coupling using alkaline catalysts system of manganese chelate and unsaturated or diketune or vinyl ether | GENERAL ELECTRIC CO. (US) | 1991-08-06 | — | — | US | disclosed |
| US-4895929-A | Process for producing polyphenylene ether, dispersing polyether in aqueous medium and heating dispersion | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0255230-A1 | Process for producing polyphenylene ethers | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| EP-0059958-B1 | PROCESS FOR PRODUCING POLYPHENYLENE OXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-06-04 | — | — | EP | disclosed |
| US-4588806-A | Polyphenylene ether resins having bimodal molecular weight distributions and method of their formation | GENERAL ELECTRIC COMPANY (US) | 1986-05-13 | — | — | US | disclosed |
| US-4385168-A | FROM OXIDATIVE POLYMERIZATION OF PHENOLIC MONOMER IN PRESENCE OF MANGANIUM SALT AND HYDROXYAZO AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-24 | — | — | US | disclosed |
| EP-0059958-A1 | Process for producing polyphenylene oxide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-09-15 | — | — | EP | disclosed |
| US-4098846-A | IMPACT STRENGTH | GENERAL ELECTRIC COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4054553-A | MANGANESE COMPLEX CATALYST | GENERAL ELECTRIC COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-3972851-A | Preparation of polyphenylene oxide using a manganese(II) ortho-hydroxyarene-oxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
| US-3965069-A | Polyphenylene oxide is prepared using a mixture of manganese chelates as a catalyst | GENERAL ELECTRIC COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3962180-A | COPPER, MANGANESE OR COBALT AND AN AMINE CATALYST | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1976-06-08 | — | — | US | disclosed |
| US-3956242-A | Preparation of polyphenylene oxide using a manganese (II) ω-hydroxyoxime chelate reaction promoter | GENERAL ELECTRIC COMPANY (US) | 1976-05-11 | — | — | US | disclosed |