Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 3/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8252773 | 0.98 | AOC3 (0.48) | AOC3PANK3MEN1KMT2AMAPT | |
| SCHEMBL8245080 | 0.86 | CYP11B1 (0.56) | AOC3PANK3MEN1KMT2AMAPT | |
| SCHEMBL5234572 | 0.81 | PANK3 (0.55) | AOC3PANK3MEN1KMT2AHRH3 | |
| SCHEMBL9908392 | 0.81 | HRH3 (0.53) | AOC3MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL2608886 | 0.80 | AOC3 (0.42) | AOC3MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL8429477 | 0.79 | CYP1A2 (0.54) | AOC3MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL345439 | 0.79 | ENPP2 (0.45) | AOC3PANK3MEN1KMT2AMAPT | |
| SCHEMBL12601594 | 0.78 | AOC3 (0.55) | AOC3MAPTUBE2TALDH1A1LMNA | |
| SCHEMBL3722859 | 0.78 | RET (0.41) | AOC3PANK3MEN1KMT2AUBE2T | |
| SCHEMBL12217555 | 0.77 | HRH3 (0.49) | AOC3MAPTUBE2TALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |
| US-7300936-B2 | α-(N-sulfonamido)acetamide derivatives as β-amyloid inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-27 | — | — | US | disclosed |