Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8256546 | 0.80 | USP2 (0.40) | CA2MAOBMAPT | |
| SCHEMBL7499699 | 0.79 | AKR1B1 (0.40) | CA2MAOBAKR1B1P2RY6TMEM97 | |
| SCHEMBL8257337 | 0.79 | AHR (0.41) | CA2AKR1B1P2RY6FFAR1MAPT | |
| SCHEMBL13862088 | 0.79 | CA2 (0.39) | CA2MAPT | |
| SCHEMBL14367864 | 0.77 | CA2 (0.55) | CA2 | |
| SCHEMBL17644228 | 0.76 | CA2 (0.40) | CA2MAOBAKR1B1P2RY6TMEM97 | |
| SCHEMBL1167587 | 0.73 | CHRNB4 (0.42) | AKR1B1MAPT | |
| SCHEMBL9983626 | 0.70 | HRH3 (0.43) | CA2MAOBAKR1B1GRM2DRD2 | |
| SCHEMBL8259596 | 0.70 | BACE1 (0.37) | CA2MAOBAKR1B1FFAR1GRM2 | |
| SCHEMBL8256379 | 0.68 | ADRB1 (0.44) | MAPTDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |