Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368316 | 0.92 | KDM4E (0.57) | HRH3KDM4EALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL20564261 | 0.84 | EBP (0.53) | HRH3LTA4HCYP2D6CYP1A2CYP2C9 | |
| SCHEMBL14418361 | 0.81 | CHRNB2 (0.55) | LTA4HKEAP1NFE2L2KDM4EALDH1A1 | |
| SCHEMBL9101297 | 0.81 | MAPT (0.57) | LTA4HKDM4EALDH1A1CYP2C9LMNA | |
| SCHEMBL7533707 | 0.81 | NPC1 (0.54) | LTA4HKDM4EALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL11534933 | 0.79 | APP (0.46) | KDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1640720 | 0.79 | HRH3 (0.59) | HRH3LTA4HKEAP1NFE2L2KDM4E | |
| SCHEMBL12774576 | 0.78 | HRH3 (0.50) | HRH3LTA4HKEAP1NFE2L2KDM4E | |
| SCHEMBL2089558 | 0.78 | NPC1 (0.59) | LTA4H | |
| SCHEMBL18120853 | 0.77 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | SANOLI-AVENTIS (FR) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | MAP3K7, MAPKAPK2, MAPK7 | HRH3 4454/4885LTA4H 4630/4885KEAP1 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.