Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CCR3 | P51677 | 3/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14392349 | 1.00 | KMT2A (0.55) | KMT2ASSTR3POLBALDH1A1CCR3 | |
| SCHEMBL14368821 | 0.91 | SSTR3 (0.53) | KMT2ASSTR3POLBALDH1A1CCR3 | |
| SCHEMBL14392348 | 0.91 | SSTR3 (0.53) | KMT2ASSTR3POLBALDH1A1CCR3 | |
| SCHEMBL14368967 | 0.91 | KMT2A (0.52) | KMT2ASSTR3POLBALDH1A1CCR3 | |
| SCHEMBL14392690 | 0.90 | SSTR3 (0.50) | KMT2ASSTR3POLBALDH1A1CCR3 | |
| SCHEMBL14368968 | 0.90 | TSHR (0.52) | KMT2ASSTR3ALDH1A1CCR3F10 | |
| SCHEMBL4552939 | 0.90 | TSHR (0.52) | KMT2ASSTR3ALDH1A1CCR3F10 | |
| SCHEMBL14392358 | 0.90 | TSHR (0.52) | KMT2ASSTR3ALDH1A1CCR3F10 | |
| SCHEMBL14368825 | 0.90 | SSTR3 (0.50) | KMT2ASSTR3POLBALDH1A1CCR3 | |
| SCHEMBL4423112 | 0.89 | KDM4E (0.47) | KMT2ASSTR3ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | OPRL1, OPRM1, SIGMAR1 | KMT2A 3736/4885SSTR3 306/4885POLB 4668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.