Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.32 |
| ▸ | DRD4 | P21917 | 4/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14369080 | 1.00 | CCR3 (0.32) | CCR3DRD4TMEM97SIGMAR1VNN1 | |
| SCHEMBL14369077 | 0.85 | NPC1 (0.33) | CCR3DRD4TMEM97SIGMAR1 | |
| SCHEMBL5662634 | 0.83 | CCR3 (0.40) | CCR3 | |
| SCHEMBL14369084 | 0.80 | DPP4 (0.32) | DRD4TMEM97SIGMAR1 | |
| SCHEMBL14369085 | 0.80 | DPP4 (0.32) | DRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4425347 | 0.79 | DPP4 (0.31) | DRD4TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4435220 | 0.79 | DPP4 (0.31) | DRD4TMEM97SIGMAR1 | |
| SCHEMBL14394400 | 0.79 | CA1 (0.38) | CCR3 | |
| SCHEMBL14369108 | 0.78 | CCR3 (0.39) | CCR3 | |
| SCHEMBL14368642 | 0.78 | CCR3 (0.40) | CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259888-A1 | Novel Compounds | OPRL1, OPRM1, SIGMAR1 | CCR3 247/4885DRD4 1256/4885TMEM97 906/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.