Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273822 | 0.87 | TP53 (0.48) | TP53MAPTSMN1; SMN2HPNALDH1A1 | |
| SCHEMBL9440385 | 0.77 | NPC1 (0.48) | TP53MAPTSMN1; SMN2HPNALDH1A1 | |
| SCHEMBL2843939 | 0.75 | NPC1 (0.70) | TP53MAPTSMN1; SMN2HPNALDH1A1 | |
| SCHEMBL29426944 | 0.72 | IDO1 (0.43) | KMT2AHPGDMEN1CYP1A2CYP2C19 | |
| SCHEMBL1307260 | 0.72 | IDO1 (0.43) | KMT2AHPGDMEN1CYP1A2CYP2C19 | |
| SCHEMBL6565665 | 0.72 | TP53 (0.70) | TP53MAPTSMN1; SMN2HPNALDH1A1 | |
| SCHEMBL6565595 | 0.71 | TP53 (0.65) | TP53MAPTSMN1; SMN2HPNALDH1A1 | |
| SCHEMBL8079370 | 0.70 | UTRN (0.47) | TP53MAPTSMN1; SMN2HPNALDH1A1 | |
| SCHEMBL8070088 | 0.70 | NPY5R (0.41) | TP53MAPTSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12758410 | 0.69 | KDM4E (0.63) | TP53MAPTSMN1; SMN2HPNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276601-B2 | Method and preparing fused oxazinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-7276601-B2 | Method and preparing fused oxazinones | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |