Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | C1R | P00736 | 1/20 | 0.46 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079370 | 0.82 | UTRN (0.47) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL2333007 | 0.81 | RAB9A (0.69) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL11338188 | 0.78 | MAPT (0.51) | NPC1RAB9ATP53MAPTSMN1; SMN2 | |
| SCHEMBL14370229 | 0.77 | TP53 (0.53) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL913895 | 0.76 | NPC1 (0.70) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL914149 | 0.75 | RAB9A (0.61) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL11381710 | 0.75 | UTRN (0.52) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL11336027 | 0.75 | NPC1 (0.56) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL6567424 | 0.74 | ELANE (0.62) | NPC1RAB9AALDH1A1KDM4EMEN1 | |
| SCHEMBL6563910 | 0.74 | HPN (0.56) | NPC1RAB9AALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6009670-A | — | — | None | — | — | JP | disclosed |
| JP-H069670-A | PHOSPHONIC ACID DIESTER DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1994-01-18 | — | — | JP | disclosed |