SCHEMBL14370321

SCHEMBL14370321

CC(=O)Oc1ccc(OC(=O)c2ccc(OC(=O)c3ccc(C)cc3)cc2)c(C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.57
KMT2A Q03164 6/20 0.52
PRSS1 P07477 1/20 0.49
ACR P10323 1/20 0.49
GBA1 P04062 1/20 0.48
MEN1 O00255 2/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
ESR1 P03372 1/20 0.46
PGR P06401 1/20 0.46
CHRM2 P08172 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
AR P10275 1/20 0.46
CHRM1 P11229 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14484181 1.00 LMNA (0.57) LMNAKMT2APRSS1ACRGBA1
SCHEMBL14370325 1.00 LMNA (0.57) LMNAKMT2APRSS1ACRGBA1
SCHEMBL14407745 0.97 LMNA (0.56) LMNAKMT2AGBA1MEN1KDM4E
SCHEMBL14484385 0.96 LMNA (0.54) LMNAKMT2APRSS1ACRGBA1
SCHEMBL31086822 0.96 MAPT (0.50) LMNAKMT2AKDM4EPOLBMAPT
SCHEMBL10449007 0.96 MAPT (0.50) LMNAKMT2AKDM4EPOLBMAPT
SCHEMBL14016851 0.93 KMT2A (0.58) LMNAKMT2APRSS1ACRGBA1
SCHEMBL15590279 0.91 LMNA (0.56) LMNAKMT2APRSS1ACRMEN1
SCHEMBL14407756 0.90 KMT2A (0.55) LMNAKMT2APRSS1ACRGBA1
SCHEMBL14407748 0.90 KMT2A (0.55) LMNAKMT2APRSS1ACRGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7288297-B2 Optical compensation plate, polarizing plate using the same and image display apparatus using the same NITTO DENKO CORPORATION (JP) 2007-10-30 US disclosed
US-7288297-B2 Optical compensation plate, polarizing plate using the same and image display apparatus using the same NITTO DENKO CORPORATION (JP) 2007-10-30 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-7270855-B2 Optical film, method for manufacturing the same, and phase difference film and polarizing plate using the same NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed