SCHEMBL14484385

SCHEMBL14484385

CC(=O)Oc1ccc(OC(=O)c2ccc(OC(=O)c3ccc(C)cc3)cc2)cc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
KMT2A Q03164 8/20 0.53
PRSS1 P07477 1/20 0.50
ACR P10323 1/20 0.50
GBA1 P04062 1/20 0.49
MEN1 O00255 2/20 0.48
GAA P10253 2/20 0.47
HPGD P15428 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
ALDH1A1 P00352 3/20 0.45
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
KDM4E B2RXH2 2/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14484181 0.96 LMNA (0.57) LMNAKMT2APRSS1ACRGBA1
SCHEMBL14370325 0.96 LMNA (0.57) LMNAKMT2APRSS1ACRGBA1
SCHEMBL14370321 0.96 LMNA (0.57) LMNAKMT2APRSS1ACRGBA1
SCHEMBL14407745 0.93 LMNA (0.56) LMNAKMT2AGBA1MEN1GAA
SCHEMBL31086822 0.91 MAPT (0.50) LMNAKMT2AKDM4EPOLBMAPT
SCHEMBL10449007 0.91 MAPT (0.50) LMNAKMT2AKDM4EPOLBMAPT
SCHEMBL14016851 0.91 KMT2A (0.58) LMNAKMT2APRSS1ACRGBA1
SCHEMBL15590279 0.87 LMNA (0.56) LMNAKMT2APRSS1ACRMEN1
SCHEMBL18636180 0.87 KMT2A (0.54) LMNAKMT2APRSS1ACRGBA1
SCHEMBL12735576 0.86 PRSS1 (0.54) LMNAKMT2APRSS1ACRGBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7235283-B2 Optical compensation plate and deflecting plate using the same NITTO DENKO CORPORATION (JP) 2007-06-26 US disclosed
US-7235283-B2 Optical compensation plate and deflecting plate using the same NITTO DENKO CORPORATION (JP) 2007-06-26 US disclosed