Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | KDM1A | O60341 | 3/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375091 | 1.00 | MGLL (0.47) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL4875448 | 0.83 | MGLL (0.52) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL14197111 | 0.83 | TP53 (0.53) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL4882624 | 0.83 | TP53 (0.53) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL4879529 | 0.83 | MGLL (0.52) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL14197109 | 0.83 | MGLL (0.52) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL5382696 | 0.82 | KMT2A (0.36) | NPC1TP53MAPTTSHRRAB9A | |
| SCHEMBL4875453 | 0.82 | MGLL (0.51) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL14197159 | 0.82 | MGLL (0.51) | MGLLNPC1ALDH1A1TP53MAPT | |
| SCHEMBL14197113 | 0.82 | LMNA (0.48) | MGLLNPC1ALDH1A1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279494-B2 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | PFIZER INC. (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279494-B2 | Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues | PFIZER INC. (US) | 2007-10-09 | — | — | US | disclosed |