Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | APEX1 | P27695 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 2/20 | 0.63 |
| ▸ | BLM | P54132 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CDK2 | P24941 | 2/20 | 0.44 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14370739 | 0.89 | MAPT (0.79) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL15555870 | 0.82 | MAPT (0.59) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL17069803 | 0.78 | MAPT (0.63) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL17069804 | 0.78 | MAPT (0.79) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL15560234 | 0.78 | MAPT (0.79) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL12171250 | 0.77 | MAPT (1.00) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL14370775 | 0.77 | PTPN11 (0.58) | MAPTGAAKDM4EALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL11281961 | 0.74 | ALDH1A1 (0.51) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL12171193 | 0.74 | MAPT (0.68) | MAPTGAAKDM4EALDH1A1KMT2A | |
| SCHEMBL12171206 | 0.72 | MAPT (0.87) | MAPTGAAKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7288680-B2 | Benzotropolone derivatives and modulation of inflammatory response | WELLGEN, INC. (US) | 2007-10-30 | — | — | US | disclosed |