SCHEMBL14372091

SCHEMBL14372091

CCc1cc(Cl)cc(CC)c1C1=C(OS(C)(=O)=O)[C@]2(CC[C@H](OC)CC2)NC1=O

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ACACB O00763 5/20 0.38
ACACA Q13085 5/20 0.38
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12724476 0.93 ACACB (0.38) ACACBACACA
SCHEMBL13288571 0.87 ACACB (0.37) ACACBACACA
SCHEMBL14490572 0.85 ACACB (0.34) ACACBACACA
SCHEMBL14372084 0.83 ACACB (0.40) ACACBACACADPP4
SCHEMBL14400352 0.83 ACACB (0.42) ACACBACACADPP4
SCHEMBL10309533 0.82 ACACB (0.40) ACACBACACA
SCHEMBL14372086 0.82 ACACB (0.39) ACACBACACADPP4
SCHEMBL14372083 0.81 ACACB (0.52) ACACBACACADPP4
SCHEMBL14372081 0.81 ACACB (0.52) ACACBACACADPP4
SCHEMBL13096258 0.81 THRB (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070244007-A1 Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2007-10-18 US disclosed
US-20070244007-A1 Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives BAYER CROPSCIENCE AG (DE) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244007-A1 Cis-Alkoxyspiro-Substituted Tetramic Acid Derivatives AGXT, PAOX, DDT ACACB 823/4885ACACA 516/4885DPP4 1094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.