SCHEMBL14372123

SCHEMBL14372123

CC1(C)CC(/N=C/c2ccccc2)CC(C)(C)N1O

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 12/20 0.43
ACHE P22303 11/20 0.43
BCHE P06276 9/20 0.41
KMT2A Q03164 3/20 0.36
RAB9A P51151 1/20 0.35
MAPT P10636 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29686857 0.84 BACE1 (0.43) BACE1ACHEBCHEKMT2ARAB9A
SCHEMBL16564659 0.78 LMNA (0.43) BACE1ACHEBCHEKMT2ARAB9A
SCHEMBL16564654 0.78 BACE1 (0.43) BACE1ACHEBCHEKMT2ARAB9A
SCHEMBL17953032 0.73 BACE1 (0.39) BACE1ACHEBCHERAB9ALMNA
SCHEMBL24849809 0.73 GAA (0.41) GAAL3MBTL1
SCHEMBL14372146 0.72 KMT2A (0.35) BACE1ACHEKMT2A
SCHEMBL2726398 0.70 BACE1 (0.61) BACE1ACHEBCHEKMT2AMAPT
SCHEMBL2726396 0.70 BACE1 (0.61) BACE1ACHEBCHEKMT2AMAPT
SCHEMBL15172984 0.70 BACE1 (0.61) BACE1ACHEBCHEKMT2AMAPT
SCHEMBL15172985 0.70 BACE1 (0.61) BACE1ACHEBCHEKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070231744-A1 Holographic recording medium KABUSHIKI KAISHA TOSHIBA (JP) 2007-10-04 US disclosed
US-20070231744-A1 Holographic recording medium KABUSHIKI KAISHA TOSHIBA (JP) 2007-10-04 US disclosed