Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.61 |
| ▸ | ACHE | P22303 | 14/20 | 0.61 |
| ▸ | BCHE | P06276 | 11/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726398 | 1.00 | BACE1 (0.61) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL15172985 | 1.00 | BACE1 (0.61) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL15172984 | 1.00 | BACE1 (0.61) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL8416726 | 0.91 | KMT2A (0.58) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL8416725 | 0.91 | KMT2A (0.58) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL8415734 | 0.91 | KMT2A (0.63) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL8415735 | 0.91 | KMT2A (0.63) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL23560085 | 0.90 | BACE1 (0.53) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL29055199 | 0.90 | BACE1 (0.53) | BACE1ACHEBCHEKMT2ALMNA | |
| SCHEMBL29055200 | 0.90 | BACE1 (0.53) | BACE1ACHEBCHEKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635551-B1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED N-(BENZYL)CYCLOPROPANAMINES BY IMINE HYDROGENATION | BAYER CROPSCIENCE AG (DE) | 2018-05-02 | — | — | EP | disclosed |
| US-9260378-B2 | Process for the preparation of substituted N-(benzyl)cyclopropanamines by imine hydrogenation | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-02-16 | — | — | US | disclosed |
| EP-2635551-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED N-(BENZYL)CYCLOPROPANAMINES BY IMINE HYDROGENATION | Bayer Cropscience AG (DE) | 2013-09-11 | — | — | EP | disclosed |
| US-20130217910-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED N-(BENZYL)CYCLOPROPANAMINES BY IMINE HYDROGENATION | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2013-08-22 | — | — | US | disclosed |
| WO-2012059585-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED N-(BENZYL)CYCLOPROPANAMINES BY IMINE HYDROGENATION | BAYER CROPSCIENCE AG (DE) | 2012-05-10 | — | — | WO | disclosed |
| EP-0714885-B1 | Preparation process of aminoacetamide derivative | EISAI CO LTD (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0714885-A2 | Preparation process of aminoacetamide derivative | EISAI CHEMICAL CO., LTD. (JP) | 1996-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217910-A1 | PROCESS FOR THE PREPARATION OF SUBSTITUTED N-(BENZYL)CYCLOPROPANAMINES BY IMINE HYDROGENATION | DHPS, PNMT, INMT | BACE1 1282/4885ACHE 1535/4885BCHE 229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.