Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 8/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.72 |
| ▸ | ATM | Q13315 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | F2R | P25116 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14373497 | 0.85 | CXCR3 (1.00) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14373500 | 0.83 | CXCR3 (0.82) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14470582 | 0.80 | CXCR3 (0.77) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14373544 | 0.80 | CXCR3 (0.80) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14373502 | 0.79 | CXCR3 (0.65) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL5463756 | 0.79 | CXCR3 (1.00) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14373506 | 0.78 | CXCR3 (1.00) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14373512 | 0.76 | RAB9A (0.73) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14373565 | 0.74 | RAB9A (0.78) | CXCR3RAB9ANPC1KMT2AATM | |
| SCHEMBL14758273 | 0.74 | CXCR3 (1.00) | CXCR3RAB9ANPC1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | CXCR3 4743/4885RAB9A 1111/4885NPC1 234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.