Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leminoprazole SCHEMBL29895760 | 1.00 | ATP4A (0.39) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| Leminoprazole SCHEMBL143740 | 1.00 | ATP4A (0.39) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| Leminoprazole SCHEMBL19086179 | 0.99 | ATP4A (0.38) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| SCHEMBL3689535 | 0.86 | ATP4A (0.52) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| SCHEMBL30637598 | 0.86 | ATP4A (0.52) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| SCHEMBL13999615 | 0.85 | TAAR1 (0.36) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| SCHEMBL9695352 | 0.85 | PDE5A (0.38) | RAB9ASMN1; SMN2NPC1ALDH1A1BACE1 | |
| SCHEMBL10726467 | 0.84 | ATP4A (0.51) | ATP4AATP4BRAB9ASMN1; SMN2POLB | |
| SCHEMBL9395758 | 0.84 | ATP4A (0.39) | ATP4AATP4BRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10520560 | 0.83 | ATP4A (0.38) | ATP4AATP4BRAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2754 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11986554-B2 | Orally disintegrating compositions | DEXCEL PHARMA TECHNOLOGIES LTD. (IL) | 2024-05-21 | — | — | US | claimed |
| CN-116603063-A | New use of proton pump inhibitor | 中日友好医院(中日友好临床医学研究所) | 2023-08-18 | — | — | CN | claimed |
| US-20230248758-A1 | METHODS OF TREATING UPPER GASTROINTESTINAL DISORDERS IN PPI REFRACTORY GERD | IRONWOOD PHARMACEUTICALS INC (US) | 2023-08-10 | — | — | US | claimed |
| CN-116407503-A | Blank liposome composition with pentacyclic triterpene compound as membrane material, and preparation method and application thereof | 复旦大学 | 2023-07-11 | — | — | CN | claimed |
| EP-3337456-B1 | LIPOSOMES WITH GINSENOSIDE AS MEMBRANE MATERIAL AND PREPARATIONS AND USE THEREOF | SHANGHAI GINPOSOME PHARMATECH CO LTD (CN) | 2022-10-26 | — | — | EP | claimed |
| US-11419834-B2 | Methods for treating diseases or infections caused by or associated with H. pylori using a halogenated salicylanilide | RHODE ISLAND HOSPITAL (US) | 2022-08-23 | — | — | US | claimed |
| US-20220133777-A1 | METHODS OF TREATING UPPER GASTROINTESTINAL DISORDERS IN PPI REFRACTORY GERD | IRONWOOD PHARMACEUTICALS INC (US) | 2022-05-05 | — | — | US | claimed |
| US-20220125730-A1 | METHOD OF MANUFACTURING AN ORALLY DISINTIGRATING TABLET | DEXCEL PHARMA TECHNOLOGIES LTD. (IL) | 2022-04-28 | — | — | US | claimed |
| US-20210290662-A1 | METHODS OF TREATING UPPER GASTROINTESTINAL DISORDERS IN PPI REFRACTORY GERD | IRONWOOD PHARMACEUTICALS INC (US) | 2021-09-23 | — | — | US | claimed |
| CN-107428726-B | Process for preparing optically active proton pump inhibitor compounds | 国立大学法人东京大学 | 2021-03-16 | — | — | CN | claimed |
| US-5731002-A | ANTISECRETORY | ASTRA AKTIEBOLAG (SE) | 1998-03-24 | — | — | US | claimed |
| EP-0621035-B1 | 2-[[2-(N-isobutyl-N-methyl)amino] benzylsulfinyl]benzimidazole as antomicrobial agent against Helicobacter pylori | NIPPON CHEMIPHAR CO (JP) | 1997-07-16 | — | — | EP | claimed |
| WO-1997012580-A2 | NOVEL COMPOSITION CONTAINING AN ACID-LABILE BENZIMIDAZOLE AND PROCESS FOR ITS PREPARATION | PHARMA PASS LLC (US) | 1997-04-10 | — | — | WO | claimed |
| WO-1997002039-A1 | ANTIBACTERIAL SYNERGISTIC COMPOSITION COMPRISING RIFABUTIN | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-01-23 | — | — | WO | claimed |
| WO-1997002261-A1 | A PROCESS FOR THE OPTICAL PURIFICATION OF ENANTIOMERICALLY ENRICHED BENZIMIDAZOLE DERIVATIVES | ASTRA AKTIEBOLAG (SE) | 1997-01-23 | — | — | WO | claimed |
| US-5576341-A | TREATING INFECTIONS CAUSED BY CAMPYLOBACTER | NIPPON CHEMIPHAR CO., LTD. (JP) | 1996-11-19 | — | — | US | claimed |
| CN-1122109-A | Veterinary composition containing proton pump inhibitor | ASTRA AB (SE) | 1996-05-08 | — | — | CN | claimed |
| EP-0696921-A1 | VETERINARY COMPOSITION CONTAINING A PROTON PUMP INHIBITOR | Astra Aktiebolag (SE) | 1996-02-21 | — | — | EP | claimed |
| WO-1994025070-A1 | VETERINARY COMPOSITION CONTAINING A PROTON PUMP INHIBITOR | ASTRA AKTIEBOLAG (SE) | 1994-11-10 | — | — | WO | claimed |
| EP-0621035-A1 | 2[[2-(N-isobutyl-N-methyl)amino]-benzylsulfinyl]benzimidazole as antimicrobial agent against Helicobacter pylori | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-10-26 | — | — | EP | claimed |