Leminoprazole

Leminoprazole

SCHEMBL19086179

CC(C)CN(C)c1ccccc1C[S+]([O-])c1nc2ccccc2[nH]1.S

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP4A P20648 1/20 0.38
ATP4B P51164 1/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 2/20 0.38
NPC1 O15118 1/20 0.38
TAAR1 Q96RJ0 1/20 0.36
ALDH1A1 P00352 3/20 0.33
BACE1 P56817 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
DDAH1 O94760 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leminoprazole SCHEMBL143739 0.99 ATP4A (0.39) ATP4AATP4BRAB9ASMN1; SMN2POLB
Leminoprazole SCHEMBL29895760 0.99 ATP4A (0.39) ATP4AATP4BRAB9ASMN1; SMN2POLB
Leminoprazole SCHEMBL143740 0.99 ATP4A (0.39) ATP4AATP4BRAB9ASMN1; SMN2POLB
SCHEMBL30637598 0.85 ATP4A (0.52) ATP4AATP4BRAB9ASMN1; SMN2POLB
SCHEMBL3689535 0.85 ATP4A (0.52) ATP4AATP4BRAB9ASMN1; SMN2POLB
SCHEMBL13999615 0.84 TAAR1 (0.36) ATP4AATP4BRAB9ASMN1; SMN2POLB
SCHEMBL9695352 0.84 PDE5A (0.38) RAB9ASMN1; SMN2NPC1ALDH1A1BACE1
SCHEMBL10726467 0.83 ATP4A (0.51) ATP4AATP4BRAB9ASMN1; SMN2POLB
SCHEMBL9395758 0.83 ATP4A (0.39) ATP4AATP4BRAB9ASMN1; SMN2NPC1
SCHEMBL10520560 0.82 ATP4A (0.38) ATP4AATP4BRAB9ASMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2521531-B1 SKIN LIGHTENING COMPOSITIONS ELC MAN LLC (US) 2017-07-12 EP claimed