Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14347592 | 1.00 | KMT2A (0.46) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL14374465 | 0.91 | KMT2A (0.43) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL14347625 | 0.91 | KMT2A (0.43) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL6745420 | 0.78 | ERCC1 (0.54) | KMT2AMEN1CYP1A2ALDH1A1NPSR1 | |
| SCHEMBL13381411 | 0.76 | ALDH1A1 (0.56) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL10386822 | 0.75 | KDM4E (0.57) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL14375950 | 0.72 | KDM4E (0.42) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL3196733 | 0.72 | ALDH1A1 (0.52) | KMT2AMEN1CYP1A2ALDH1A1MAPT | |
| SCHEMBL14347613 | 0.71 | KDM4E (0.49) | KMT2ACYP1A2ALDH1A1MAPTKDM4E | |
| SCHEMBL13381409 | 0.71 | MAPT (0.68) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307170-B2 | Epindolidione pigments | CLARIANT FINANCE (BVI) LIMITED (VG) | 2007-12-11 | — | — | US | disclosed |