Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6745420 | 0.78 | ERCC1 (0.54) | KDM4EHSD17B10KMT2AMEN1CYP1A2 | |
| SCHEMBL10386822 | 0.75 | KDM4E (0.57) | KDM4EKMT2AMEN1CYP1A2LMNA | |
| SCHEMBL14347592 | 0.72 | KMT2A (0.46) | KDM4EHSD17B10KMT2AMEN1CYP1A2 | |
| SCHEMBL14374079 | 0.72 | KMT2A (0.46) | KDM4EHSD17B10KMT2AMEN1CYP1A2 | |
| SCHEMBL14375942 | 0.72 | SMN1; SMN2 (0.43) | KMT2AMEN1CYP1A2LMNAALDH1A1 | |
| SCHEMBL14375940 | 0.72 | SMN1; SMN2 (0.47) | KDM4EUSP2HSD17B10KMT2AMEN1 | |
| SCHEMBL14347625 | 0.71 | KMT2A (0.43) | KMT2AMEN1CYP1A2LMNAALDH1A1 | |
| SCHEMBL14374465 | 0.71 | KMT2A (0.43) | KMT2AMEN1CYP1A2LMNAALDH1A1 | |
| SCHEMBL14375915 | 0.71 | RAB9A (0.48) | KDM4EHSD17B10KMT2AMEN1CYP1A2 | |
| SCHEMBL14375920 | 0.69 | HPGD (0.41) | KMT2AMEN1CYP1A2RORCLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |