Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 13/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CD40 | P25942 | 1/20 | 0.36 |
| ▸ | CD40LG | P29965 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374683 | 0.93 | PHLPP2 (0.42) | ENPP2PHLPP2CYP1A2CYP3A4HPGD | |
| SCHEMBL13994861 | 0.91 | ENPP2 (0.49) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14374581 | 0.90 | PHLPP2 (0.44) | ENPP2PHLPP2CYP1A2CD40CD40LG | |
| SCHEMBL14374918 | 0.89 | ENPP2 (0.46) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14400895 | 0.89 | ENPP2 (0.48) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14374585 | 0.88 | ENPP2 (0.45) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13900494 | 0.88 | CD40 (0.46) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13915882 | 0.88 | ENPP2 (0.44) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14374727 | 0.87 | ENPP2 (0.42) | ENPP2PHLPP2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14374580 | 0.86 | PHLPP2 (0.44) | ENPP2PHLPP2CYP1A2CD40CD40LG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070227388-A1 | Tetrakisazo Compound, Coloring Matter for Recording, Ink Composition and Colored Article | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2007-10-04 | — | — | US | disclosed |