Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.42 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426455 | 1.00 | CA2 (0.42) | CA2CA1DPP7CA7CA14 | |
| SCHEMBL14347683 | 1.00 | CA2 (0.42) | CA2CA1DPP7CA7CA14 | |
| SCHEMBL14375598 | 0.91 | CA1 (0.34) | CA2CA1CA7CA14 | |
| SCHEMBL8427642 | 0.91 | CA1 (0.34) | CA2CA1CA7CA14 | |
| SCHEMBL14348117 | 0.91 | CA1 (0.34) | CA2CA1CA7CA14 | |
| SCHEMBL14117580 | 0.85 | CA2 (0.42) | CA2CA1DPP7CA7CA14 | |
| SCHEMBL8244390 | 0.85 | CA2 (0.42) | CA2CA1DPP7CA7CA14 | |
| SCHEMBL14348572 | 0.81 | ACACB (0.32) | ALDH1A1MAPK1 | |
| SCHEMBL14348551 | 0.81 | ALDH1A1 (0.31) | ALDH1A1GAAHPGD | |
| SCHEMBL8426467 | 0.81 | ACACB (0.32) | ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304056-B2 | Succinoylamino lactams as inhibitors of Aβ protein production | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-12-04 | — | — | US | disclosed |