Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 5/20 | 0.72 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 3/20 | 0.47 |
| ▸ | CSF1R | P07333 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27098679 | 0.82 | RAB9A (0.78) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL14375954 | 0.82 | ALDH1A1 (0.51) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL14028049 | 0.80 | ALDH1A1 (0.72) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL12394275 | 0.80 | RAB9A (0.72) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL12394222 | 0.79 | ALDH1A1 (0.71) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL19748106 | 0.79 | RAB9A (0.76) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL14375927 | 0.79 | RAB9A (0.76) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL14375804 | 0.79 | ALDH1A1 (0.64) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL12394223 | 0.78 | RAB9A (0.70) | ALDH1A1RAB9ANPC1KDM4EMAPT | |
| SCHEMBL12394229 | 0.78 | RAB9A (0.70) | ALDH1A1RAB9ANPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |
| US-7279576-B2 | Anti-cancer medicaments | DECIPHERA PHARMACEUTICALS, LLC (US) | 2007-10-09 | — | — | US | disclosed |