Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | HPGD | P15428 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL17254516 | 0.99 | KDM4E (0.38) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL15908096 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL16476444 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAAGLA | |
| Bromide SCHEMBL15901676 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAAGLA | |
| Iodide SCHEMBL17254509 | 0.87 | KDM4E (0.37) | KDM4EALDH1A1HPGDGAAGLA | |
| Iodide SCHEMBL29959754 | 0.86 | KDM4E (0.39) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL15908095 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL15901247 | 0.84 | KDM4E (0.44) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL16476450 | 0.82 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAAGLA | |
| SCHEMBL15908086 | 0.81 | CYP1A2 (0.39) | KDM4EALDH1A1HPGDGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723743-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2019-08-14 | — | — | EP | disclosed |
| EP-2723743-B1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2019-08-14 | — | — | EP | disclosed |
| US-9185913-B2 | 10H-benzo[g]pteridine-2,4-dione derivatives, method for the production thereof, and use thereof | TRIOPTOTEC GMBH (DE) | 2015-11-17 | — | — | US | disclosed |
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TRIOPTOTEC GMBH (DE) | 2014-07-17 | — | — | US | disclosed |
| WO-2012175730-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | TriOpto Tec GmbH (DE) | 2012-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200220-A1 | 10H-BENZO[G]PTERIDINE-2,4-DIONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | DHPS, DOHH, DPYD | KDM4E 495/4885ALDH1A1 1162/4885HPGD 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.