SCHEMBL14378409

SCHEMBL14378409

O=C(O)c1ccccc1C(=O)c1ccc2sc3ccc(Cc4ccc(CO)cc4)cc3c2c1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.48
CDC25A P30304 1/20 0.48
HSD17B10 Q99714 1/20 0.48
LMNA P02545 1/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 2/20 0.44
CYP1A2 P05177 1/20 0.42
AKR1C3 P42330 3/20 0.42
TSHR P16473 1/20 0.42
HNF4A P41235 1/20 0.42
ATM Q13315 1/20 0.41
NR4A1 P22736 1/20 0.40
PRNP P04156 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
PRSS12 P56730 1/20 0.38
LTC4S Q16873 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14124816 0.89 AKR1C3 (0.56) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL14124784 0.86 USP2 (0.49) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL2330767 0.82 CDC25B (0.58) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL14124723 0.78 AKR1C3 (0.68) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL14378405 0.76 SRD5A2 (0.48) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL14124740 0.75 CDC25A (0.40) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL14124724 0.73 AKR1C3 (0.70) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL3164435 0.73 CALM1 (0.50) LMNACYP1A2HNF4A
SCHEMBL14378417 0.73 CDC25B (0.45) CDC25BCDC25AHSD17B10LMNAALDH1A1
SCHEMBL14124821 0.72 AKR1C3 (0.56) CDC25BCDC25AHSD17B10LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282160-B2 Light emitting device and fluorescent material MITSUBISHI CHEMICAL CORPORATION (JP) 2007-10-16 US disclosed