SCHEMBL14380997

SCHEMBL14380997

CC(C)c1csc(C(C)C)c1Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.33
GABRB1 P18505 1/20 0.33
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13919783 0.76 CYP2A6 (0.32)
SCHEMBL13919790 0.76 GPR35 (0.31)
SCHEMBL21737251 0.74 SMN1; SMN2 (0.31)
SCHEMBL23890446 0.71 GABRA1 (0.30) GABRA1GABRB2
SCHEMBL21451842 0.71 GABRA1 (0.41) GABRA1GABRB1GABRB2
SCHEMBL18721967 0.71 GABRA1 (0.34) GABRA1GABRB2
SCHEMBL14404765 0.71
Hydrochloric Acid SCHEMBL9634974 0.70 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL13341967 0.69 KDM4E (0.36)
SCHEMBL25128822 0.68 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7285565-B2 Benzamides and related inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-10-23 US disclosed