Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.52 |
| ▸ | GLS | O94925 | 6/20 | 0.52 |
| ▸ | GLS2 | Q9UI32 | 5/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13846851 | 0.73 | NR1H4 (0.64) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL13846866 | 0.70 | NR1H4 (0.86) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL18545405 | 0.70 | NR1H4 (0.86) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL13846877 | 0.67 | NR1H4 (1.00) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL1249981 | 0.66 | POLB (0.77) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL1249980 | 0.66 | POLB (0.77) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL12892002 | 0.66 | POLB (0.77) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL14325640 | 0.65 | RAB9A (0.68) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL1250446 | 0.65 | NR1H4 (0.70) | NPC1RAB9APOLBNR1H4GLS | |
| SCHEMBL12891998 | 0.65 | NR1H4 (0.70) | NPC1RAB9APOLBNR1H4GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585541-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-11-14 | — | — | EP | disclosed |