Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.77 |
| ▸ | NPC1 | O15118 | 4/20 | 0.77 |
| ▸ | RAB9A | P51151 | 4/20 | 0.77 |
| ▸ | NR1H4 | Q96RI1 | 8/20 | 0.74 |
| ▸ | PPARA | Q07869 | 1/20 | 0.74 |
| ▸ | GLS | O94925 | 5/20 | 0.73 |
| ▸ | GLS2 | Q9UI32 | 4/20 | 0.73 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1249981 | 1.00 | POLB (0.77) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL1249980 | 1.00 | POLB (0.77) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL13846866 | 0.87 | NR1H4 (0.86) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL18545405 | 0.87 | NR1H4 (0.86) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL13846859 | 0.86 | NPC1 (0.69) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL13846877 | 0.85 | NR1H4 (1.00) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL18545596 | 0.77 | TCF4 (0.68) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL12009043 | 0.77 | TCF4 (0.68) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL14325640 | 0.76 | RAB9A (0.68) | POLBNPC1RAB9ANR1H4PPARA | |
| SCHEMBL5672232 | 0.76 | MYC (0.77) | RAB9AHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| US-7879893-B2 | Zinc binding ligand; sustained release of insulin | NOVO NORDISK A/S (DK) | 2011-02-01 | — | — | US | disclosed |
| US-20090123563-A1 | Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand | NOVO NORDISK A/S (DK) | 2009-05-14 | — | — | US | disclosed |
| US-20090123563-A1 | Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand | NOVO NORDISK A/S (DK) | 2009-05-14 | — | — | US | disclosed |
| EP-1585541-B1 | PHARMACEUTICAL COMPOSITIONS COMPRISING INSULIN AND LEGENDS OF INSULIN HEXAMER | NOVO NORDISK AS (DK) | 2007-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090123563-A1 | Pharmaceutical Preparations Comprising Insulin, Zinc Ions and Zinc-Binding Ligand | IAPP, IRS1, HBB | POLB 2360/4885NPC1 3787/4885RAB9A 1951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.