Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | CDK8 | P49336 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL669442 | 0.89 | EPHX2 (0.70) | SMN1; SMN2EPHX2IDO1MEN1KMT2A | |
| SCHEMBL14384837 | 0.89 | TLR8 (0.62) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23894756 | 0.87 | SMN1; SMN2 (0.59) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B | |
| Nitrogen SCHEMBL28799837 | 0.86 | SMN1; SMN2 (0.66) | SMN1; SMN2EPHX2IDO1MEN1KMT2A | |
| SCHEMBL6516221 | 0.86 | KMT2A (0.73) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL14384680 | 0.85 | MTNR1A (0.66) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL24168621 | 0.85 | MTNR1A (0.58) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL23894755 | 0.85 | KMT2A (0.58) | SMN1; SMN2MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL29817773 | 0.85 | MEN1 (0.67) | SMN1; SMN2EPHX2MEN1KMT2ATRPV1 | |
| SCHEMBL11582431 | 0.84 | TP53 (0.57) | EPHX2TRPV1BRAFKDRMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130743-A2 | CAPREOMYCIN DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | ARRAY BIOPHARMA, INC. (US) | 2007-11-15 | — | — | WO | disclosed |