Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | IDO1 | P14902 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.61 |
| ▸ | KIF11 | P52732 | 2/20 | 0.59 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrogen SCHEMBL28799837 | 0.96 | SMN1; SMN2 (0.66) | EPHX2SMN1; SMN2IDO1ALDH1A1TRPV1 | |
| SCHEMBL14384397 | 0.89 | SMN1; SMN2 (0.58) | EPHX2SMN1; SMN2IDO1ALDH1A1TRPV1 | |
| SCHEMBL23059791 | 0.89 | SMN1; SMN2 (0.58) | EPHX2SMN1; SMN2IDO1ALDH1A1TRPV1 | |
| SCHEMBL18409061 | 0.89 | NPC1 (0.65) | EPHX2SMN1; SMN2IDO1ALDH1A1TRPV1 | |
| SCHEMBL16349508 | 0.86 | SMN1; SMN2 (0.68) | EPHX2SMN1; SMN2IDO1ALDH1A1KIF11 | |
| SCHEMBL19227674 | 0.85 | SMN1; SMN2 (0.59) | EPHX2SMN1; SMN2IDO1ALDH1A1TRPV1 | |
| SCHEMBL14546864 | 0.84 | SMN1; SMN2 (0.71) | EPHX2SMN1; SMN2IDO1ALDH1A1TRPV1 | |
| SCHEMBL5544653 | 0.84 | SMN1; SMN2 (0.71) | EPHX2SMN1; SMN2IDO1ALDH1A1KIF11 | |
| SCHEMBL3415035 | 0.84 | EPHX2 (0.66) | EPHX2SMN1; SMN2ALDH1A1TRPV1KIF11 | |
| SCHEMBL9784355 | 0.84 | SMN1; SMN2 (0.71) | EPHX2SMN1; SMN2IDO1ALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563043-A | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | 葛兰素史密斯克莱知识产权发展有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-103930407-B | Aminopyrimidine derivatives useful as modulators of kinase activity | 默克专利有限公司 | 2019-02-26 | — | — | CN | claimed |
| CN-106946796-A | Aminopyridine derivative as modulators of kinase activity | 默克专利有限公司 | 2017-07-14 | — | — | CN | claimed |
| CN-103906730-A | Parp inhibitors | HOFFMANN LA ROCHE | 2014-07-02 | — | — | CN | claimed |
| US-4766243-A | Electrophilic fluorination of aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-08-23 | — | — | US | claimed |
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | INCYTE CORPORATION (US) | 2026-04-09 | — | — | US | disclosed |
| US-20250333419-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF WRN | INCYTE CORPORATION (US) | 2025-10-30 | — | — | US | disclosed |
| US-20250215006-A1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF WRN | INCYTE CORPORATION (US) | 2025-07-03 | — | — | US | disclosed |
| CN-115650970-B | Thiazolinone compound and preparation method and application thereof | 江西科技师范大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-118255686-A | Fluorine-containing trans-phenyl cyclopropylamine derivative, and preparation method and application thereof | 郑州大学 | 2024-06-28 | — | — | CN | disclosed |
| CN-113462278-B | Varnish composition, method for producing polyimide resin, and additive | 东京应化工业株式会社 | 2024-06-07 | — | — | CN | disclosed |
| EP-4326721-A1 | SPIROCYCLIC IMIDAZOLIDINONES AND IMIDAZOLIDINEDIONES FOR TREATMENT OF LIGHT CHAIN AMYLOIDOSIS | Protego Biopharma, Inc. (US) | 2024-02-28 | — | — | EP | disclosed |
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| US-6235730-B1 | ANTICHOLESTEROL AGENT, ANTILIPEMIC AGENT | JAPAN TOBACCO, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1252068-A | 3-piperidyl-4-oxoquinazoline derivatives and pharmaceutical compositions containing the same | JAPAN TOBACCO INC (JP) | 2000-05-03 | — | — | CN | disclosed |
| EP-0970954-A1 | 3-PIPERIDYL-4-OXOQUINAZOLINE DERIVATIVES AND MEDICINCAL COMPOSITIONS CONTAINING THE SAME | JAPAN TOBACCO INC. (JP) | 2000-01-12 | — | — | EP | disclosed |
| EP-0246061-B1 | A BENZOYLUREA DERIVATIVE AND ITS PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4766243-A | Electrophilic fluorination of aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1988-08-23 | — | — | US | disclosed |
| EP-0246061-A2 | A benzoylurea derivative and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094767-A1 | 2,3-Dihydro-6-nitroimidazo[2,1-b]oxazoles | NR2C2, NR4A3, NR4A2 | EPHX2 3662/4885SMN1; SMN2 3985/4885IDO1 3181/4885 |
| US-20260098041-A1 | FUSED BICYCLIC PYRIMIDONES AS WRN INHIBITORS | WRN, POLR1A, REV1 | EPHX2 2786/4885SMN1; SMN2 1169/4885IDO1 1654/4885 |
| US-20250333419-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF WRN | WRN, BLM, RECQL | EPHX2 2907/4885SMN1; SMN2 1568/4885IDO1 448/4885 |
| US-20250215006-A1 | TRICYCLIC COMPOUNDS AS INHIBITORS OF WRN | WRN, BLM, RECQL | EPHX2 3049/4885SMN1; SMN2 1990/4885IDO1 471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.