Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 6/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.35 |
| ▸ | FURIN | P09958 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186302 | 1.00 | TPSAB1 (0.38) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL14385292 | 1.00 | TPSAB1 (0.38) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL2735620 | 1.00 | TPSAB1 (0.38) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL10186970 | 1.00 | TPSAB1 (0.38) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL2735621 | 1.00 | TPSAB1 (0.38) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL14394101 | 0.91 | SIRT2 (0.43) | TPSAB1SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL12235966 | 0.89 | SIRT2 (0.40) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL10186972 | 0.89 | SIRT2 (0.40) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL12235967 | 0.89 | SIRT2 (0.40) | TPSAB1SIRT2SIRT1SIRT3ITGB3 | |
| SCHEMBL2735622 | 0.86 | TPSAB1 (0.30) | TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115164-A9 | AMINO ACID SURROGATES FOR PEPTIDIC CONSTRUCTS | PALATIN TECHNOLOGIES INC (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007115164-A2 | AMINO ACID SURROGATES FOR PEPTIDIC CONSTRUCTS | PALATIN TECHNOLOGIES, INC. (US) | 2007-10-11 | — | — | WO | disclosed |