Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 12/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 12/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 5/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | FURIN | P09958 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12235966 | 1.00 | SIRT2 (0.40) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL10186972 | 1.00 | SIRT2 (0.40) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL14394101 | 0.90 | SIRT2 (0.43) | SIRT2SIRT1SIRT3TPSAB1 | |
| SCHEMBL14385292 | 0.89 | TPSAB1 (0.38) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL2735620 | 0.89 | TPSAB1 (0.38) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL10186970 | 0.89 | TPSAB1 (0.38) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL14385293 | 0.89 | TPSAB1 (0.38) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL186302 | 0.89 | TPSAB1 (0.38) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL2735621 | 0.89 | TPSAB1 (0.38) | SIRT2SIRT1SIRT3TPSAB1ITGB3 | |
| SCHEMBL13435351 | 0.83 | SIRT2 (0.39) | SIRT2SIRT1SIRT3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110263818-A1 | Peptidic Constructs with Amino Acid Surrogates | PALATIN TECHNOLOGIES, INC. (US) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263818-A1 | Peptidic Constructs with Amino Acid Surrogates | ARGLU1, QRFPR, ARG1 | SIRT2 3293/4885SIRT1 3416/4885SIRT3 2986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.