Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 9/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.76 |
| ▸ | AKR1B1 | P15121 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385526 | 0.87 | ALOX15 (0.73) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL14385345 | 0.86 | ALOX15 (1.00) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL14385530 | 0.84 | ALOX15 (0.71) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL14385352 | 0.81 | ALOX15 (0.62) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL30298319 | 0.77 | ALOX15 (0.76) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL14385538 | 0.77 | ALOX15 (0.72) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL30109400 | 0.71 | MAPK1 (0.64) | ALOX15ALOX12CA2CA4HSD17B10 | |
| SCHEMBL14385528 | 0.71 | ALOX15 (0.69) | ALOX15ALOX12AKR1B1HTTMEN1 | |
| SCHEMBL14385537 | 0.71 | ALOX15 (0.45) | ALOX15ALOX12AKR1B1CA2CA4 | |
| SCHEMBL30076189 | 0.70 | ALOX15 (0.60) | ALOX15ALOX12AKR1B1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086895-A9 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007086895-A2 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-08-02 | — | — | WO | disclosed |