Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.62 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695064 | 0.85 | TPMT (0.58) | ALOX15ALOX12AKR1B1HSD17B10TPMT | |
| SCHEMBL17866818 | 0.83 | ALOX15 (0.68) | ALOX15ALOX12AKR1B1TDP1HTT | |
| SCHEMBL29469603 | 0.81 | ALOX15 (0.66) | ALOX15ALOX12AKR1B1TDP1HTT | |
| SCHEMBL14385526 | 0.81 | ALOX15 (0.73) | ALOX15ALOX12AKR1B1HSD17B10TDP1 | |
| SCHEMBL14385364 | 0.81 | ALOX15 (0.76) | ALOX15ALOX12AKR1B1HSD17B10HTT | |
| SCHEMBL30927163 | 0.79 | ALOX15 (0.56) | ALOX15ALOX12TPMTTDP1HTT | |
| SCHEMBL129971 | 0.79 | ALOX15 (0.56) | ALOX15ALOX12TPMTTDP1HTT | |
| SCHEMBL9418420 | 0.78 | TDP1 (0.64) | ALOX15ALOX12HSD17B10TPMTTDP1 | |
| SCHEMBL31177143 | 0.76 | ALOX15 (1.00) | ALOX15ALOX12AKR1B1TDP1HTT | |
| SCHEMBL29398700 | 0.76 | ALOX15 (1.00) | ALOX15ALOX12AKR1B1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086895-A9 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007086895-A2 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | PINNACLE PHARMACEUTICALS (US) | 2007-08-02 | — | — | WO | disclosed |