Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437707 | 0.87 | LMNA (0.39) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3746174 | 0.84 | LMNA (0.32) | LMNA | |
| SCHEMBL512168 | 0.84 | LMNA (0.32) | LMNA | |
| SCHEMBL22497045 | 0.83 | LMNA (0.39) | LMNASMN1; SMN2ALDH1A1JAK3 | |
| SCHEMBL23130508 | 0.82 | LMNA (0.38) | LMNASMN1; SMN2ALDH1A1JAK3 | |
| SCHEMBL22441070 | 0.82 | LMNA (0.38) | LMNASMN1; SMN2ALDH1A1JAK3 | |
| SCHEMBL22441066 | 0.82 | LMNA (0.38) | LMNASMN1; SMN2ALDH1A1JAK3 | |
| SCHEMBL30419013 | 0.81 | JAK3 (0.36) | LMNASMN1; SMN2JAK3 | |
| SCHEMBL650847 | 0.80 | LMNA (0.36) | LMNASMN1; SMN2 | |
| SCHEMBL652815 | 0.80 | LMNA (0.36) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023693-A1 | METHYLPYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |