Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.43 |
| ▸ | TUBB | P07437 | 4/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14387572 | 0.90 | TUBB1 (0.46) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL13931749 | 0.87 | TUBB1 (0.61) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL14001681 | 0.87 | TUBB1 (0.52) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL14387460 | 0.84 | TUBB1 (0.49) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL10073867 | 0.83 | SMN1; SMN2 (0.45) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL10073863 | 0.80 | CYP1A2 (0.50) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL13844083 | 0.80 | DYRK1A (0.43) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL13931888 | 0.77 | TUBB1 (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL13844093 | 0.76 | PRKAG1 (0.40) | TUBB1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL18554248 | 0.76 | BCHE (0.56) | TUBB1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007137196-A2 | TUBULIN BINDING ANTI CANCER COMPOUNDS AND PRODRUGS THEREOF | THRESHOLD PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |