SCHEMBL10073863

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10073867	0.85	SMN1; SMN2 (0.45)	FLT3HDAC6CDK2PRKAG1PRKAA1
	SCHEMBL176882	0.84	PRKAG1 (0.66)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL13931749	0.83	TUBB1 (0.61)	RAB9ANPC1L3MBTL1CASP3SENP8
	SCHEMBL14001681	0.83	TUBB1 (0.52)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL4482588	0.83	FLT3 (0.65)	FLT3CDK2ALDH1A1HRH1RAB9A
	SCHEMBL18554248	0.81	BCHE (0.56)	FLT3CYP3A4HDAC6CDK2PRKAG1
	SCHEMBL10073860	0.81	PRKAG1 (0.44)	FLT3KMT2AHDAC6CDK2PRKAG1
	SCHEMBL17782665	0.81	FLT3 (0.47)	FLT3TSHRKMT2AMEN1CDK2
	SCHEMBL14387460	0.80	TUBB1 (0.49)	FLT3CDK2PRKAG1PRKAA1PRKAB1
	SCHEMBL13794487	0.80	L3MBTL1 (0.47)	FLT3KMT2AMEN1HDAC6CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.