Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513123 | 0.87 | NPY5R (0.48) | BACE1STSNAMPTGPR119SMARCA2 | |
| SCHEMBL23355043 | 0.85 | MCOLN3 (0.50) | STSGPR119ALDH1A1LMNAMEN1 | |
| SCHEMBL5334602 | 0.85 | BACE1 (0.46) | BACE1STSNAMPTGPR119SMARCA2 | |
| SCHEMBL5336031 | 0.85 | STS (0.48) | BACE1STSNAMPTGPR119SMARCA2 | |
| SCHEMBL5336255 | 0.84 | MCOLN3 (0.62) | STSMEN1KMT2AMCOLN2MCOLN3 | |
| SCHEMBL5340137 | 0.83 | STS (0.61) | BACE1STSGPR119SMARCA2SMARCA4 | |
| SCHEMBL6603122 | 0.83 | GPR119 (0.46) | BACE1STSNAMPTGPR119SMARCA2 | |
| SCHEMBL23379772 | 0.82 | TGFBR1 (0.52) | BACE1STSNAMPTALDH1A1MAPT | |
| SCHEMBL5335920 | 0.81 | BACE1 (0.49) | BACE1NAMPTGPR119SMARCA2SMARCA4 | |
| SCHEMBL23355076 | 0.81 | KMT2A (0.59) | STSALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291619-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-11-06 | — | — | US | disclosed |