SCHEMBL14388352

SCHEMBL14388352

NOC(=O)CC(N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 9/20 0.48
GRIK2 Q13002 6/20 0.48
GRM1 Q13255 2/20 0.48
GRM2 Q14416 2/20 0.48
SLC7A5 Q01650 1/20 0.46
PTGS1 P23219 1/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
SLC1A1 P43005 5/20 0.43
GGT1 P19440 4/20 0.43
GRIA4 P48058 4/20 0.42
GRIK3 Q13003 4/20 0.42
GRIK5 Q16478 4/20 0.42
SLC1A3 P43003 3/20 0.41
SLC1A2 P43004 3/20 0.41
GRIA2 P42262 3/20 0.41
GRIA1 P42261 2/20 0.41
GRM8 O00222 1/20 0.41
GRM6 O15303 1/20 0.41
GRIN2D O15399 1/20 0.41
GRIN3B O60391 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14882533 1.00 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL27787856 0.98 GRIK1 (0.46) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL29011629 0.80 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL1078699 0.80
SCHEMBL291079 0.80
SCHEMBL25491149 0.80 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL19107032 0.80 GRIK1 (0.48) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL28296858 0.80 TSHR (0.31)
SCHEMBL151676 0.78 SLC1A1 (0.58) GRIK1GRIK2GRM1GRM2SLC7A5
SCHEMBL2018995 0.78 SLC1A1 (0.58) GRIK1GRIK2GRM1GRM2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294672-B2 Method to form polymeric materials by reverse suspension/emulsion polymerization and compositions formed using that method POLYMER CHEMISTRY INNOVATIONS, INC. (US) 2007-11-13 US disclosed