Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 4/20 | 0.58 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 9/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.48 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.45 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.45 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536243 | 1.00 | SLC1A1 (0.58) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL151676 | 1.00 | SLC1A1 (0.58) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL6506409 | 0.98 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL2238405 | 0.98 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL933300 | 0.98 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL23851398 | 0.98 | SLC1A1 (0.56) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| Hydrochloric Acid SCHEMBL25212271 | 0.96 | SLC1A1 (0.55) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL9449386 | 0.86 | SLC1A1 (0.54) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL7359265 | 0.86 | SLC1A1 (0.54) | SLC1A1SLC7A5GRIK1GRIK2GRM1 | |
| SCHEMBL5050477 | 0.85 | SLC1A1 (0.53) | SLC1A1SLC7A5GRIK1GRIK2GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999251-A | Synthetic method of aspoxicillin sodium | 海南海灵化学制药有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-116262736-B | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-117897388-A | BTK protein degradation agent | 广州麓鹏制药有限公司 | 2024-04-16 | — | — | CN | disclosed |
| US-20240058457-A1 | BTK DEGRADER | NEWAVE PHARMACEUTICAL INC. (US) | 2024-02-22 | — | — | US | disclosed |
| EP-4263552-A1 | BTK DEGRADER | Guangzhou Lupeng Pharmaceutical Company Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| US-11780853-B2 | Substituted N-pyrimidin-4-yl-3-aminopyrrolo[3,4-C]pyrazoles as protein kinase C inhibitors | PFIZER INC. (US) | 2023-10-10 | — | — | US | disclosed |
| CN-116829949-A | Compositions for detecting or measuring analytes | 伯蒂斯有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116262736-A | Novel oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| US-20230127805-A1 | PROCESS FOR THE PREPARATION OF (R)-4-(1-(6-(4-(TRIFLUOROMETHYL)BENZYL)-6-AZASPIRO[2.5]OCTANE-5-CARBOXAMIDO)-CYCLOPROPYL) BENZOIC ACID OR A SALT THEREOF | ROTTAPHARM BIOTECH S.R.L. (IT) | 2023-04-27 | — | — | US | disclosed |
| US-20230127805-A1 | PROCESS FOR THE PREPARATION OF (R)-4-(1-(6-(4-(TRIFLUOROMETHYL)BENZYL)-6-AZASPIRO[2.5]OCTANE-5-CARBOXAMIDO)-CYCLOPROPYL) BENZOIC ACID OR A SALT THEREOF | ROTTAPHARM BIOTECH S.R.L. (IT) | 2023-04-27 | — | — | US | disclosed |
| CN-102958932-A | 5-HT receptor modulators and methods of use thereof | ABBVI INC | 2013-03-06 | — | — | CN | disclosed |
| US-20120202809-A1 | NOVEL N-PYRIMIDIN-4-YL-3-AMINO-PYRROLO[3,4-C]PYRAZOLE DERIVATIVES AS PKC KINASE INHIBITORS | PFIZER INC. | 2012-08-09 | — | — | US | disclosed |
| US-20120202809-A1 | NOVEL N-PYRIMIDIN-4-YL-3-AMINO-PYRROLO[3,4-C]PYRAZOLE DERIVATIVES AS PKC KINASE INHIBITORS | PFIZER INC. | 2012-08-09 | — | — | US | disclosed |
| US-8183255-B2 | N-pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazole derivatives as PKC kinase inhibitors | PFIZER, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183255-B2 | N-pyrimidin-4-yl-3-amino-pyrrolo[3,4-c]pyrazole derivatives as PKC kinase inhibitors | PFIZER, INC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-20110130382-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-06-02 | — | — | US | disclosed |
| US-20100130501-A1 | NOVEL 3-AMINO-PYRROLO[3,4-C]PYRAZOLE-5(1H, 4H, 6H) CARBALDEHYDE DERIVATIVES | PFIZER INC. | 2010-05-27 | — | — | US | disclosed |
| US-20100130501-A1 | NOVEL 3-AMINO-PYRROLO[3,4-C]PYRAZOLE-5(1H, 4H, 6H) CARBALDEHYDE DERIVATIVES | PFIZER INC. | 2010-05-27 | — | — | US | disclosed |
| WO-2008096260-A1 | 3-AMINO-PYRROLO[3,4-C] PYRAZOLE- 5 (1H, 4H, 6H) CARBALDEHYDE DERIVATIVES AS PKC INHIBITORS | PFIZER INC. (US) | 2008-08-14 | — | — | WO | disclosed |
| US-7253194-B2 | Compounds and inhibitors of phospholipases | THE UNIVERSITY OF QUEENSLAND (AU) | 2007-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11780853-B2 | Substituted N-pyrimidin-4-yl-3-aminopyrrolo[3,4-C]pyrazoles as protein kinase C inhibitors | PRKCB, PRKCA, PRKCQ | SLC1A1 2736/4885SLC7A5 3872/4885GRIK1 442/4885 |
| US-20230127805-A1 | PROCESS FOR THE PREPARATION OF (R)-4-(1-(6-(4-(TRIFLUOROMETHYL)BENZYL)-6-AZASPIRO[2.5]OCTANE-5-CARBOXAMIDO)-CYCLOPROPYL) BENZOIC ACID OR A SALT THEREOF | BACH1, ADH1C, ADH1A | SLC1A1 3233/4885SLC7A5 3475/4885GRIK1 2302/4885 |
| US-20110130382-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | HTR4, HTR1A, HTR1D | SLC1A1 408/4885SLC7A5 3046/4885GRIK1 133/4885 |
| US-20240058457-A1 | BTK DEGRADER | BTK, LYN, SYK | SLC1A1 4855/4885SLC7A5 4789/4885GRIK1 3418/4885 |
| US-20100130501-A1 | NOVEL 3-AMINO-PYRROLO[3,4-C]PYRAZOLE-5(1H, 4H, 6H) CARBALDEHYDE DERIVATIVES | DPP3, IAPP, GPR119 | SLC1A1 668/4885SLC7A5 1420/4885GRIK1 2212/4885 |
| US-20120202809-A1 | NOVEL N-PYRIMIDIN-4-YL-3-AMINO-PYRROLO[3,4-C]PYRAZOLE DERIVATIVES AS PKC KINASE INHIBITORS | PRKCB, PRKCA, PRKCE | SLC1A1 2244/4885SLC7A5 2898/4885GRIK1 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.