SCHEMBL28296858

SCHEMBL28296858

NOC(=O)CC(N)C(N)=O

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
CTH P32929 1/20 0.31
CBS P35520 1/20 0.31
THPO P40225 1/20 0.31
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1078699 0.80
SCHEMBL14882533 0.80 GRIK1 (0.48)
SCHEMBL291079 0.80
SCHEMBL14388352 0.80 GRIK1 (0.48)
SCHEMBL29808913 0.78 ALOX15 (0.33) ALOX15BLMPMP22KMT2A
SCHEMBL16838810 0.78 TSHR (0.42) TSHRKMT2A
SCHEMBL27787856 0.78 GRIK1 (0.46)
SCHEMBL29115441 0.78 TSHR (0.42) TSHRKMT2A
SCHEMBL2610090 0.78 GRIK1 (0.34)
SCHEMBL16838812 0.78 TSHR (0.42) TSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109715185-A Water soluble and chemically stable glucagon peptides 印第安纳大学研究及科技有限公司 2019-05-03 CN disclosed